Description

Thieno[3,2-D]Pyrimidin-4-Amine, 2-(Chloromethyl)- (9Ci) is a high-value heterocyclic organic compound featuring a fused thienopyrimidine core with a reactive chloromethyl substituent. This structure makes it a critical pharmaceutical intermediate and key building block for medicinal chemistry research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel active molecules.

Application

• Pharmaceutical Intermediate: Serves as a versatile precursor in the synthesis of potential kinase inhibitors, anticancer agents, and other biologically active small molecules.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Acts as a building block for creating novel herbicides, fungicides, or insecticides with thienopyrimidine-based activity.
• Organic Electronic Materials: Investigated as a component in the development of organic semiconductors or charge-transport materials due to its conjugated heterocyclic system.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and cellular pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	Thieno[3,2-D]Pyrimidin-4-Amine, 2-(Chloromethyl)- (9Ci)
CAS No.	77294-21-4
Molecular Formula	C7H6ClN3S
Molecular Weight	199.66 g/mol
Synonyms	2-(Chloromethyl)thieno[3,2-d]pyrimidin-4-amine; 4-Amino-2-(chloromethyl)thieno[3,2-d]pyrimidine; 2-(Chloromethyl)-4-aminothieno[3,2-d]pyrimidine; Thieno[3,2-d]pyrimidin-4-amine, 2-(chloromethyl)-; 77294-21-4; 2-Chloromethyl-thieno[3,2-d]pyrimidin-4-ylamine
EINECS	Contact for details

Quality Control

Our production of Thieno[3,2-D]Pyrimidin-4-Amine, 2-(Chloromethyl)- adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized and tested using advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.