Description

Xorphanol is a synthetic opioid analgesic compound with significant research and development interest. Its primary value lies in its potent pharmacological profile, making it a critical intermediate for advanced pharmaceutical studies and the development of novel pain management solutions. This compound is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on neuropharmacology and analgesic discovery.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate in the synthesis and study of novel opioid receptor agonists and antagonists.
• Analgesic Drug Discovery: Used in preclinical research for developing new classes of potent pain relievers with potentially improved therapeutic indices.
• Neuropharmacology Studies: Employed in biochemical assays and animal models to investigate opioid receptor binding, signal transduction, and central nervous system effects.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in forensic and pharmaceutical analysis.
• Fine Chemical Synthesis: Utilized as a specialized building block for the custom synthesis of complex molecules for clinical and non-clinical evaluation.

Basic Information

Product Name	Xorphanol
CAS No.	77287-89-9
Molecular Formula	C24H31NO4
Molecular Weight	397.51 g/mol
Synonyms	Xorphanol; (-)-Xorphanol; (5R,9R,13S,14S)-Xorphanol; WIN 44441; 3,4-Dimethoxy-17-methylmorphinan-6β,14-diol; 6β,14-Dihydroxy-3,4-dimethoxy-17-methylmorphinan
EINECS	Contact for details

Quality Control

Our Xorphanol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP guidelines where applicable for pharmaceutical intermediates, ensuring traceability and documentation for regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.