Description

(S)-1,2,3,4-Tetrahydro-6,7-Dimethoxy-1-Methyl-2-Propylisoquinoline is a high-purity, chiral tetrahydroisoquinoline derivative of significant interest in advanced organic synthesis. This compound matters as a key chiral building block and intermediate for the research and development of novel pharmaceutical agents, particularly those targeting the central nervous system. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating enantiomerically pure compounds.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral scaffold in the synthesis of potential drug candidates, especially for neurological and cardiovascular applications.
• Asymmetric Synthesis: Used as a starting material or ligand precursor in catalytic asymmetric reactions to induce chirality in target molecules.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and library synthesis for lead optimization.
• Reference Standard: Acts as an analytical standard for method development and quality control in chiral analysis (e.g., HPLC, SFC).
• Fine Chemical Synthesis: Utilized in the multi-step synthesis of complex natural products and specialty chemicals requiring the tetrahydroisoquinoline core.
• Agrochemical Development: Investigated as an intermediate for novel, biologically active compounds in crop protection research.

Basic Information

Product Name	(S)-1,2,3,4-Tetrahydro-6,7-Dimethoxy-1-Methyl-2-Propylisoquinoline
CAS No.	77280-40-1
Molecular Formula	C15H23NO2
Molecular Weight	249.35 g/mol
Synonyms	(S)-1,2,3,4-Tetrahydro-6,7-dimethoxy-1-methyl-2-propylisoquinoline; (S)-1-Methyl-2-propyl-1,2,3,4-tetrahydro-6,7-dimethoxyisoquinoline; (S)-6,7-Dimethoxy-1-methyl-2-propyl-1,2,3,4-tetrahydroisoquinoline; (S)-Tetrahydropapaverine derivative; (S)-THP derivative; (S)-1,2,3,4-Tetrahydro-1-methyl-2-propyl-6,7-isoquinolinediol dimethyl ether; (S)-(-)-1,2,3,4-Tetrahydro-6,7-dimethoxy-1-methyl-2-propylisoquinoline
EINECS	Contact for details

Quality Control

Our (S)-1,2,3,4-Tetrahydro-6,7-Dimethoxy-1-Methyl-2-Propylisoquinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity determination by HPLC, to ensure compliance with stringent specifications for research and development use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.