Description

Theophylline Magnesium Salicylate is a complex pharmaceutical salt combining the bronchodilator theophylline with magnesium salicylate. This compound is valued for its potential synergistic effects, offering both respiratory support and anti-inflammatory/analgesic properties in a single molecular entity. It is primarily utilized by pharmaceutical manufacturers and research institutions in the development of advanced therapeutic formulations, particularly for conditions requiring combined bronchodilation and pain or inflammation management.

Application

• Pharmaceutical Intermediates: Serves as a key active pharmaceutical ingredient (API) or precursor in the synthesis of combination drug products.
• Respiratory Therapeutics: Used in R&D for formulating medications targeting asthma, chronic obstructive pulmonary disease (COPD), and other bronchospastic conditions.
• Anti-inflammatory/Analgesic Formulations: Explored for developing drugs that address pain and inflammation, potentially with improved gastrointestinal tolerance profiles.
• Veterinary Medicine: Applicable in the development of specialized veterinary pharmaceuticals for respiratory and inflammatory conditions in animals.
• Biochemical Research: Employed as a standard or reagent in pharmacological studies investigating adenosine receptor antagonism and salicylate mechanisms.
• Controlled-Release Drug Delivery: A candidate for incorporation into sustained-release tablet or capsule formulations to provide prolonged therapeutic effect.

Basic Information

Product Name	Theophylline Magnesium Salicylate
CAS No.	77254-85-4
Molecular Formula	C20H22MgN4O9
Molecular Weight	502.72 g/mol
Synonyms	Magnesium Theophylline Salicylate; Theophylline Magnesium Salicylate Complex; 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-, compd. with magnesium 2-hydroxybenzoate (1:?); Theophylline Magnesium Salt with Salicylic Acid; Magnesium Theophyllinate Salicylate; Theophylline-Mg-Salicylate; Theophylline Magnesium Salicylate Hydrate (if applicable); 77254-85-4
EINECS	Contact for details

Quality Control

Our Theophylline Magnesium Salicylate is produced and tested under a strict quality management system. We ensure compliance with relevant pharmaceutical guidelines and can supply material suitable for research and development purposes. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are provided with each batch to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	10.0% - 12.0% (as MgO)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Solubility	Sparingly soluble in water; soluble in dilute acids

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.