Description

2,2,2-Trifluoroethanol-D3 is a deuterated isotopologue of 2,2,2-trifluoroethanol (TFE), where the three hydroxyl hydrogen atoms are replaced by deuterium (CAS 77253-67-9). This isotopic labeling is critical for applications requiring precise spectroscopic analysis and mechanistic studies without interfering background signals. It is an essential reagent for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-fidelity deuterated solvents or intermediates for NMR spectroscopy, mass spectrometry, and kinetic isotope effect studies.

Application

• NMR Spectroscopy Solvent: Used as a deuterated solvent for high-resolution nuclear magnetic resonance (NMR) analysis, particularly for fluorine-19 and proton NMR studies of organic and organofluorine compounds.
• Mass Spectrometry Internal Standard: Serves as a critical internal standard or reference compound in quantitative mass spectrometry (MS) and liquid chromatography-mass spectrometry (LC-MS) to ensure analytical accuracy.
• Mechanistic Reaction Studies: Employed in kinetic isotope effect (KIE) studies to elucidate reaction mechanisms in pharmaceutical and chemical synthesis pathways.
• Deuterated Intermediate Synthesis: Acts as a key building block for the synthesis of more complex deuterium-labeled compounds in medicinal chemistry and material science.
• Polymer & Material Science Research: Utilized in the study of fluoropolymer interactions and surface properties where deuterium labeling provides unique analytical insights.

Basic Information

Product Name	2,2,2-Trifluoroethanol-D3
CAS No.	77253-67-9
Molecular Formula	C2D3F3O
Molecular Weight	103.05 g/mol
Synonyms	2,2,2-Trifluoro-1,1,1-trideuteroethanol; Deuterated Trifluoroethanol; TFE-d3; Trifluoroethanol-d3; 1,1,1-Trideutero-2,2,2-trifluoroethanol; (Trideuteriomethyl)trifluoromethanol; CF3CD2OD; Perfluoroethyl alcohol-d3
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoroethanol-D3 is produced under stringent conditions to ensure high isotopic and chemical purity, meeting the exacting requirements of analytical and synthetic applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic purity (D atom %), chemical purity by GC and NMR, and water content. We adhere to relevant quality management standards to ensure batch-to-batch consistency and reliability for your critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at room temperature (15-25°C). Due to its properties as a fluoride/strong alkali and highly volatile nature, keep away from heat, sparks, open flames, and strong oxidizing agents. Ensure containers are kept upright to prevent leakage.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms
Purity (GC)	≥ 99.0%
Isotopic Purity (D atom %)	≥ 99.0%
Water Content (KF)	≤ 0.1%
NMR Assay	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.