Description

5,6-Dimethoxy-1,2,3,4-Tetrahydro-3-Isoquinolinecarboxylic Acid Hydrochloride is a high-purity, pharmaceutically relevant organic salt used as a critical intermediate in advanced chemical synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality building blocks for their processes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex alkaloids and other bioactive molecules for drug discovery and development.
• Organic Synthesis Reagent: Used in research and production for constructing tetrahydroisoquinoline scaffolds, a privileged structure in medicinal chemistry.
• Agrochemical Research: Serves as a precursor in the development of novel crop protection agents and herbicides.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development, validation, and quality control in laboratories.
• Academic & Industrial R&D: Utilized in chemical research for studying reaction mechanisms and developing new synthetic methodologies.

Basic Information

Product Name	5,6-Dimethoxy-1,2,3,4-Tetrahydro-3-Isoquinolinecarboxylic Acid Hydrochloride
CAS No.	77141-34-5
Molecular Formula	C12H16ClNO4
Molecular Weight	273.71 g/mol
Synonyms	3-Carboxy-5,6-dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride; 5,6-Dimethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid hydrochloride; 5,6-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid HCl; 3-Isoquinolinecarboxylic acid, 1,2,3,4-tetrahydro-5,6-dimethoxy-, hydrochloride; 5,6-Dimethoxy-3,4-dihydroisoquinoline-3-carboxylic acid hydrochloride
EINECS	Contact for details

Quality Control

Our 5,6-Dimethoxy-1,2,3,4-Tetrahydro-3-Isoquinolinecarboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.