Description

7-Ethyl-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate belonging to the tetrahydroisoquinoline class of compounds. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new therapeutic agents and high-value products.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel drug candidates, particularly for central nervous system (CNS) and cardiovascular applications.
• API Synthesis: Serves as a crucial precursor in multi-step synthetic routes for complex Active Pharmaceutical Ingredients (APIs).
• Agrochemical Research: Used in the development of new pesticides and herbicides due to its bioactive isoquinoline scaffold.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and complex organic molecules.
• Academic & R&D: A valuable compound for medicinal chemistry research, process development, and method validation in laboratory settings.
• Chiral Catalyst Ligand Precursor: Potential use in the synthesis of ligands for asymmetric catalysis.

Basic Information

Product Name	7-Ethyl-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid
CAS No.	77140-96-6
Molecular Formula	C₁₂H₁₅NO₂
Molecular Weight	205.25 g/mol
Synonyms	7-Ethyl-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid; 7-Ethyl-3,4-dihydro-1H-isoquinoline-3-carboxylic acid; 7-Ethyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; 3-Carboxy-7-ethyl-1,2,3,4-tetrahydroisoquinoline; 7-Ethyl-THIQ-3-COOH; (RS)-7-Ethyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; (±)-7-Ethyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 7-Ethyl-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture. Store away from incompatible materials such as strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.