Description

7-tert-Butyl-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid is a high-purity, synthetically derived organic compound belonging to the tetrahydroisoquinoline class. This versatile chiral building block is critical for the development of advanced pharmaceutical intermediates and fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Agrochemical Research: Used as a precursor in the development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a backbone for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural product analogs and other high-value specialty chemicals.
• Academic & Industrial R&D: A valuable compound for methodological studies in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	7-tert-Butyl-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid
CAS No.	77140-81-9
Molecular Formula	C₁₄H₁₉NO₂
Molecular Weight	233.31 g/mol
Synonyms	7-tert-Butyl-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid; 7-(tert-Butyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; 3-Carboxy-7-tert-butyl-1,2,3,4-tetrahydroisoquinoline; 7-tert-Butyl-THIQ-3-COOH; 7-tert-Butyl-3-carboxytetrahydroisoquinoline; (R/S)-7-tert-Butyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 7-tert-Butyl-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.