Description

3-Thiophenecarbonyl Chloride, 2-Methoxy- (9Ci) is a high-purity, reactive organic intermediate essential for advanced chemical synthesis. Its value lies in its role as a versatile acylating agent, enabling the introduction of the 2-methoxythiophene-3-carbonyl moiety into target molecules. This compound is primarily needed by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals. CAS No. 77133-29-0.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting the central nervous system or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the thiophene scaffold contributes to biological activity.
• Material Science Research: Serves as a precursor for functionalized monomers or ligands in the development of conductive polymers, organic semiconductors, and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for creating specialty chemicals, dyes, and complex organic molecules.
• Academic & Industrial R&D: A critical reagent for methodological development in organic chemistry and for exploring new reaction pathways in heterocyclic chemistry.

Basic Information

Item	Detail
Product Name	3-Thiophenecarbonyl Chloride, 2-Methoxy- (9Ci)
CAS No.	77133-29-0
Molecular Formula	C6H5ClO2S
Molecular Weight	176.62 g/mol
Synonyms	2-Methoxythiophene-3-carbonyl chloride; 2-Methoxy-3-thenoyl chloride; 3-Thenoyl chloride, 2-methoxy-; 2-Methoxy-3-thiophenecarboxylic acid chloride; 2-Methoxythiophene-3-carboxylic acid chloride; 77133-29-0; 2-Methoxy-3-thienoyl chloride
EINECS	Contact for details

Quality Control

Our 3-Thiophenecarbonyl Chloride, 2-Methoxy- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Products undergo rigorous analytical testing, including chromatography and spectroscopic methods, to confirm identity and meet stringent impurity profiles. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity limits is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.