Description

(2R)-2,3-Dihydro-1H-Indole-2-Ylmethanol CAS NO 77122-21-5 is a chiral indoline derivative, a high-value building block in organic synthesis. Its enantiopure structure is critical for imparting specific stereochemistry in complex molecules, directly impacting their biological activity and efficacy. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and fine chemicals requiring precise chiral control.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of enantiomerically pure drugs, especially those targeting neurological and cardiovascular disorders.
• Asymmetric Catalyst Ligand Synthesis: Used to construct sophisticated ligand frameworks for transition metal catalysts in enantioselective reactions.
• Agrochemical Development: Serves as a building block for novel, stereospecific pesticides and herbicides.
• Academic & Contract Research: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.
• Fine Chemical Production: Employed in the multi-step synthesis of complex natural products and specialty chemicals.

Basic Information

Product Name	(2R)-2,3-Dihydro-1H-Indole-2-Ylmethanol
CAS No.	77122-21-5
Molecular Formula	C9H11NO
Molecular Weight	149.19 g/mol
Synonyms	(R)-Indoline-2-methanol; (2R)-Indolin-2-ylmethanol; (R)-2-(Hydroxymethyl)indoline; (R)-2,3-Dihydro-1H-indole-2-methanol; (2R)-2,3-Dihydro-1H-indole-2-carbinol; (R)-Indoline-2-ylmethanol; (R)-2-(Hydroxymethyl)-2,3-dihydro-1H-indole; (2R)-2-(Hydroxymethyl)indoline
EINECS	Contact for details

Quality Control

Our (2R)-2,3-Dihydro-1H-Indole-2-Ylmethanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high enantiomeric excess (e.e.) and chemical purity suitable for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.