Description

2-Acetamido-4-Mercaptobutanoic Acid Hydrazide is a specialized organic compound featuring both a mercapto (thiol) group and a hydrazide moiety, making it a versatile building block for chemical synthesis. This compound is valued for its role as a key intermediate in the development of pharmaceuticals, particularly in the creation of enzyme inhibitors and prodrugs. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for advanced R&D and production processes.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those targeting cysteine proteases or designed as prodrugs.
• Bioconjugation Reagent: Utilized for modifying proteins, peptides, and antibodies via its reactive thiol and hydrazide functional groups.
• Chemical Research: Serves as a valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Agrochemical Development: Used in the research and synthesis of new active ingredients for crop protection products.
• Material Science: Acts as a cross-linking agent or monomer in the development of specialized polymers and functional materials.

Basic Information

Product Name	2-Acetamido-4-Mercaptobutanoic Acid Hydrazide
CAS No.	77076-41-6
Molecular Formula	C7H15N3O3S
Molecular Weight	221.28 g/mol
Synonyms	N-Acetyl-L-homocysteine hydrazide; L-Homocysteine, N-acetyl-, hydrazide; N-Acetylhomocysteine hydrazide; 2-Acetamido-4-mercaptobutyric acid hydrazide; Ac-Hcy-NHNH2; N-Acetylhomocysteinhydrazid; (2R)-2-Acetamido-4-sulfanylbutanehydrazide
EINECS	Contact for details

Quality Control

Our 2-Acetamido-4-Mercaptobutanoic Acid Hydrazide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial use. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation of the thiol group and maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.