Description

2-(2-Chloro-Acetylamino)-6-Methyl-4,5,6,7-Tetrahydro-Benzo[B]Thiophene-3-Carboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate critical for the synthesis of complex active pharmaceutical ingredients (APIs). This compound matters because it provides a structurally defined and reactive scaffold, enabling precise chemical modifications essential for modern drug discovery and development. It is primarily needed by R&D laboratories and manufacturing facilities in the pharmaceutical and agrochemical industries, where it serves as a key building block for creating novel therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the production of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Organic Synthesis Building Block: Employed in academic and industrial research for constructing complex fused-ring systems and exploring new chemical reactions.
• API Development: Integral to the process chemistry and scale-up phases for developing new Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probe Synthesis: Used to create specialized molecules for studying biological pathways and target validation.

Basic Information

Product Name	2-(2-Chloro-Acetylamino)-6-Methyl-4,5,6,7-Tetrahydro-Benzo[B]Thiophene-3-Carboxylic Acid Ethyl Ester
CAS No.	76981-87-8
Molecular Formula	C₁₅H₁₈ClNO₃S
Molecular Weight	327.82 g/mol
Synonyms	Ethyl 2-(2-chloroacetamido)-6-methyl-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate; 2-(2-Chloroacetamido)-6-methyl-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid ethyl ester; 76981-87-8; 6-Methyl-2-[(2-chloroacetyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid ethyl ester; Ethyl 2-[(2-chloroacetyl)amino]-6-methyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate; Tetrahydrobenzothiophene derivative
EINECS	Contact for details

Quality Control

Our 2-(2-Chloro-Acetylamino)-6-Methyl-4,5,6,7-Tetrahydro-Benzo[B]Thiophene-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support development and commercial projects requiring compliance with cGMP and ICH Q7 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound may be moisture-sensitive; ensure the container is kept tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.