Description

1-(4-Bromophenyl)-2,2,2-Trifluoroethanol is a versatile fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key chiral intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where the trifluoroethanol moiety can impart desirable metabolic stability and bioavailability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with unique thermal, chemical, or surface properties.
• Catalyst & Ligand Development: Utilized in the design and synthesis of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Chemical Research & Development: A valuable reagent for method development and exploring new fluorination reactions in academic and industrial laboratories.

Basic Information

Item	Details
Product Name	1-(4-Bromophenyl)-2,2,2-Trifluoroethanol
CAS No.	76911-73-4
Molecular Formula	C8H6BrF3O
Molecular Weight	255.03 g/mol
Synonyms	4-Bromo-α-(trifluoromethyl)benzyl Alcohol; (4-Bromophenyl)(trifluoromethyl)methanol; 1-(4-Bromophenyl)-2,2,2-trifluoroethan-1-ol; α-(Trifluoromethyl)-4-bromobenzyl Alcohol; p-Bromo-α-(trifluoromethyl)benzyl Alcohol; 2,2,2-Trifluoro-1-(4-bromophenyl)ethanol; 4-Bromo-α,α,α-trifluoromethylbenzyl Alcohol
EINECS	Contact for details

Quality Control

Our 1-(4-Bromophenyl)-2,2,2-Trifluoroethanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high-purity standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. The container must be kept tightly closed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (Specific enantiomer available)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.