Description

3-(Chloromethyl)Isoquinoline Hydrochloride is a versatile and reactive organic salt primarily used as a key synthetic intermediate in advanced chemical synthesis. Its value lies in the chloromethyl group, which provides a reactive handle for further functionalization, making it a critical building block for complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of complex isoquinoline-based drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides with isoquinoline scaffolds.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic semiconductors, fluorescent dyes, and other advanced functional materials.
• Chemical Biology Probes: Utilized to develop molecular probes and tags for studying biological processes and target identification.
• Custom Synthesis and Scale-up: A starting material for contract research organizations (CROs) and CDMOs performing custom synthesis for clients.

Basic Information

Product Name	3-(Chloromethyl)Isoquinoline Hydrochloride
CAS No.	76884-33-8
Molecular Formula	C10H9Cl2N
Molecular Weight	214.09 g/mol
Synonyms	3-(Chloromethyl)isoquinoline HCl; 3-(Chloromethyl)isoquinoline hydrochloride; Isoquinoline, 3-(chloromethyl)-, hydrochloride (1:1); 3-Chloromethylisoquinoline Hydrochloride; 3-(Chloromethyl)isoquinolinium Chloride
EINECS	Contact for details

Quality Control

Our 3-(Chloromethyl)Isoquinoline Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, identity, and impurity profiles. We are committed to meeting the stringent requirements of research and development as well as scale-up production, with specifications available to support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and reactivity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.