Description

3-Amino-1H-Isoindole Hydrochloride is a versatile heterocyclic building block of significant importance in modern synthetic chemistry. Its core value lies in its bifunctional nature, featuring both an amino group and an isoindole ring system, making it a key intermediate for constructing complex molecular architectures. This compound is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the isoindole scaffold contributes to biological activity.
• Organic Synthesis Reagent: Serves as a versatile precursor for the preparation of fused polycyclic compounds, dyes, and functional materials.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development and exploring new chemical spaces in medicinal chemistry.
• Ligand and Catalyst Preparation: Utilized in the synthesis of specialized ligands for metal complexes and catalysts used in asymmetric synthesis.

Basic Information

Product Name	3-Amino-1H-Isoindole Hydrochloride
CAS No.	76644-74-1
Molecular Formula	C8H9N2·HCl
Molecular Weight	168.63 g/mol (Free base: 132.17 g/mol)
Synonyms	3-Amino-1H-isoindole HCl; 1H-Isoindol-3-amine hydrochloride; 3-Aminoisoindole hydrochloride; 3-Amino-2,3-dihydro-1H-isoindole hydrochloride; 76644-74-1; 3-Amino-1H-isoindole monohydrochloride; 3-Amino-isoindole HCl; 3-Amino-1H-isoindole, hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Amino-1H-Isoindole Hydrochloride is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption and degradation. Recommended storage temperature: 2-8°C.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.