Description

4,7,5'-Trimethylallopsoralen is a high-purity, synthetically derived psoralen derivative. This compound is valued for its role as a key intermediate and research chemical in the development of novel photochemotherapeutic agents and bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, photobiology, and dermatological research. Our product is supplied with full traceability and rigorous quality documentation to support critical R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel psoralen-based drugs for phototherapy (PUVA therapy).
• Medicinal Chemistry Research: Used as a reference standard and starting material for structure-activity relationship (SAR) studies targeting skin disorders.
• Photobiology Studies: Employed in academic and industrial research to investigate mechanisms of photosensitization and DNA cross-linking under UV light.
• Biochemical Tool Compound: Utilized in vitro to study cell cycle effects, apoptosis induction, and other photodynamic biological pathways.
• Dermatological Product Development: Acts as a precursor in formulating potential topical treatments for conditions like psoriasis, vitiligo, and cutaneous T-cell lymphoma.

Basic Information

Product Name	4,7,5'-Trimethylallopsoralen
CAS No.	76591-80-5
Molecular Formula	C14H12O4
Molecular Weight	244.24 g/mol
Synonyms	5,7,8-Trimethylallopsoralen; 4,7,5'-Trimethyl-2H-furo[2,3-h]chromen-2-one; 5,7,8-Trimethyl-2H-furo[2,3-h][1]benzopyran-2-one; Allopsoralen, 4,7,5'-trimethyl-; 5,7,8-Trimethylfuro[2,3-h]chromen-2-one
EINECS	Contact for details

Quality Control

Every batch of 4,7,5'-Trimethylallopsoralen is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for research and development purposes. A Certificate of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and identification is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.