Description

Divalproex Sodium is a stable coordination compound of sodium valproate and valproic acid, widely recognized for its therapeutic properties. This high-purity active pharmaceutical ingredient (API) is critical for ensuring the efficacy and safety of finished pharmaceutical formulations. It is primarily required by pharmaceutical manufacturers and research institutions developing and producing treatments for neurological and psychiatric disorders.

Application

• Primary Pharmaceutical Ingredient: The principal active component in the formulation of anti-epileptic and mood-stabilizing medications.
• Generic Drug Manufacturing: Serves as the key API for producing generic versions of divalproex sodium delayed-release tablets and capsules.
• Neurological Disorder Treatment: Used in medications for managing complex partial seizures, simple and complex absence seizures, and manic episodes associated with bipolar disorder.
• Migraine Prophylaxis: Incorporated into formulations intended for the prevention of migraine headaches.
• Clinical Research & Development: Employed as a reference standard and raw material in preclinical studies and clinical trials for new CNS-targeted therapies.
• Dosage Form Development: Utilized in R&D for developing novel delivery systems such as extended-release formulations to improve patient compliance.

Basic Information

Product Name	Divalproex Sodium
CAS No.	76584-70-8
Molecular Formula	C16H31NaO4
Molecular Weight	310.41 g/mol
Synonyms	Valproate Semisodium; Sodium Valproate and Valproic Acid; 2-Propylpentanoic Acid Sodium Salt; Depakote (Trade Name); Valproate Sodium; Valproic Acid Sodium Salt; Divalproex Na; Semisodium Valproate
EINECS	Contact for details

Quality Control

Our Divalproex Sodium is manufactured and tested under strict quality management systems. It is produced to meet exacting standards, including relevant pharmacopeial monographs (USP/EP). Every batch undergoes comprehensive analytical testing for identity, purity, potency, and specified impurities. A Certificate of Analysis (COA) documenting all test results is provided to ensure full traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White or almost white powder
Identification (IR)	Conforms
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 3.0%
Related Substances (HPLC)	Meets requirements
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm
Microbial Enumeration	Meets USP/EP criteria

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.