Description

4H-Pyrimido(6,1-A)Isoquinolin-4-One, 6,7-Dihydro-9,10-Dimethoxy-2-(Eth Yl(2,4,6-Trimethylphenyl)Amino)-, Hydrate (2:1) is a high-purity, complex heterocyclic organic compound with a defined hydrate structure. This compound is valued as a key advanced intermediate in the synthesis of specialized pharmaceuticals and fine chemicals, where its unique molecular framework is critical. It is primarily required by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing novel therapeutic agents and high-value chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) or cardiovascular targets.
• Organic Synthesis Research: Used in academic and industrial laboratories for studying novel heterocyclic chemistry, reaction mechanisms, and the construction of complex molecular architectures.
• Fine Chemical Production: Employed in the manufacture of high-value, low-volume specialty chemicals for agrochemicals, dyes, or material science applications.
• Biochemical Research: Potential use as a precursor or reference standard in biochemical assays and pharmacological studies to investigate enzyme inhibition or receptor binding.

Basic Information

Product Name	4H-Pyrimido(6,1-A)Isoquinolin-4-One, 6,7-Dihydro-9,10-Dimethoxy-2-(Eth Yl(2,4,6-Trimethylphenyl)Amino)-, Hydrate (2:1)
CAS No.	76536-69-1
Molecular Formula	C25H29N3O3 · ½H2O
Molecular Weight	416.52 g/mol (Anhydrous basis)
Synonyms	6,7-Dihydro-9,10-dimethoxy-2-[ethyl(2,4,6-trimethylphenyl)amino]-4H-pyrimido[6,1-a]isoquinolin-4-one hydrate (2:1); 2-[Ethyl(2,4,6-trimethylphenyl)amino]-6,7-dihydro-9,10-dimethoxy-4H-pyrimido[6,1-a]isoquinolin-4-one hemihydrate; CAS 76536-69-1; Pyrimidoisoquinolinone derivative; 4H-Pyrimido[6,1-a]isoquinolin-4-one, 6,7-dihydro-9,10-dimethoxy-2-[ethyl(2,4,6-trimethylphenyl)amino]-, hydrate (2:1).
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	2.0% - 4.0% (Theoretical for hemihydrate: ~2.16%)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.