Description

5-(Chloromethyl)Isoquinoline is a versatile and reactive heterocyclic building block, essential for advanced organic synthesis. Its value lies in the chloromethyl group, which serves as a key handle for further functionalization, enabling the construction of complex molecular architectures. This intermediate is particularly critical for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it is used to develop active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-cancer agents.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging the isoquinoline scaffold for biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed reactions and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic semiconductors, fluorescent dyes, and other functional materials.
• Chemical Biology Probes: Useful for creating tagged molecules to study biological processes and enzyme functions.
• Custom Synthesis Building Block: Provides a reactive site for coupling reactions, enabling the creation of diverse chemical libraries for screening.

Basic Information

Product Name	5-(Chloromethyl)Isoquinoline
CAS No.	76518-58-6
Molecular Formula	C10H8ClN
Molecular Weight	177.63 g/mol
Synonyms	Isoquinoline, 5-(chloromethyl)-; 5-Chloromethylisoquinoline; (Isoquinolin-5-yl)methyl chloride; 5-(Chloromethyl)isoquinoline; 76518-58-6; 5-Chloromethyl-isoquinoline; 5-(Chloromethyl)-isoquinoline
EINECS	Contact for details

Quality Control

Our 5-(Chloromethyl)Isoquinoline is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.