Description

Veradoline is a synthetic organic compound of significant interest in advanced pharmaceutical research and development. Its unique chemical structure makes it a valuable intermediate for the synthesis of novel therapeutic agents targeting the central nervous system. This high-purity compound is essential for research institutions, pharmaceutical companies, and contract development and manufacturing organizations (CDMOs) engaged in the discovery and production of new medications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential new chemical entities (NCEs) for neurological and psychiatric research.
• Preclinical Research: Used in laboratory studies to investigate pharmacological activity, metabolism, and structure-activity relationships (SAR).
• Reference Standard: Serves as a high-purity analytical standard for method development and quality control in API (Active Pharmaceutical Ingredient) manufacturing.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial production scales.
• Contract Manufacturing: Supplied to CDMOs for the production of custom pharmaceutical intermediates under cGMP conditions.

Basic Information

Product Name	Veradoline
CAS No.	76448-47-0
Molecular Formula	C24H28N2O3
Molecular Weight	392.49 g/mol
Synonyms	Veradoline; 1-[2-(Dimethylamino)ethyl]-4-(3-methoxyphenyl)-2-methyl-3,4-dihydroisoquinoline; 1-[2-(Dimethylamino)ethyl]-4-(3-methoxyphenyl)-2-methyl-1,2,3,4-tetrahydroisoquinoline; 4-(3-Methoxyphenyl)-2-methyl-1-[2-(dimethylamino)ethyl]-3,4-dihydroisoquinoline; U-62066E; U62066E; U 62066E
EINECS	Contact for details

Quality Control

Our Veradoline is manufactured and tested to meet the stringent requirements of the pharmaceutical and research industries. We employ rigorous analytical methods, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing all specifications and test results. Our quality management system supports production under current Good Manufacturing Practice (cGMP) principles for research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.