Description

Methyl 2-Bromothiophene-3-Carboxylate is a high-purity brominated thiophene derivative that serves as a critical synthetic intermediate in advanced organic chemistry. This compound is valued for its reactivity, particularly in cross-coupling reactions and as a versatile building block for constructing complex heterocyclic systems. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting the central nervous system and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the thiophene scaffold for bioactivity.
• Material Science Precursor: Employed in the creation of organic semiconductors, conductive polymers, and other advanced electronic materials due to the thiophene core.
• Cross-Coupling Reactions: Serves as an excellent substrate for Suzuki, Stille, and other palladium-catalyzed coupling reactions to form biaryl and complex conjugated systems.
• Chemical Research: A versatile reagent in academic and industrial laboratories for methodological development and the synthesis of complex organic molecules.
• Ligand and Catalyst Development: Used to synthesize novel ligands for metal catalysis and organocatalysts.

Basic Information

Product Name	Methyl 2-Bromothiophene-3-Carboxylate
CAS No.	76360-43-5
Molecular Formula	C6H5BrO2S
Molecular Weight	221.07 g/mol
Synonyms	Methyl 2-bromo-3-thiophenecarboxylate; 2-Bromothiophene-3-carboxylic acid methyl ester; 3-Thiophenecarboxylic acid, 2-bromo-, methyl ester; 2-Bromo-3-methoxycarbonylthiophene; Methyl 2-bromothiophene-3-carboxylate; 2-Bromo-3-(methoxycarbonyl)thiophene
EINECS	Contact for details

Quality Control

Our Methyl 2-Bromothiophene-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee consistency and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.