Description

Ethyl (S)-(3-Methyl-4-Oxo-5-Piperidin-1-Ylthiazolidin-2-Ylidene)Acetate is a high-purity, chiral thiazolidinone derivative with significant synthetic utility. This compound serves as a versatile and critical pharmaceutical intermediate for the development of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical industries for its role in constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Organic Synthesis Reagent: Used in advanced organic chemistry for constructing thiazolidinone and piperidine-containing scaffolds.
• Research & Development (R&D): Essential for medicinal chemistry programs in academic and industrial labs for structure-activity relationship (SAR) studies.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for new chemical entities (NCEs).
• Asymmetric Synthesis: Utilized as a chiral auxiliary or precursor in stereoselective synthesis due to its defined (S)-configuration.

Basic Information

Product Name	Ethyl (S)-(3-Methyl-4-Oxo-5-Piperidin-1-Ylthiazolidin-2-Ylidene)Acetate
CAS No.	76333-71-6
Molecular Formula	C13H20N2O3S
Molecular Weight	284.37 g/mol
Synonyms	(S)-Ethyl 2-(3-methyl-4-oxo-5-(piperidin-1-yl)thiazolidin-2-ylidene)acetate; Ethyl (S)-2-(3-methyl-4-oxo-5-(1-piperidinyl)-2-thiazolidinylidene)acetate; 76333-71-6; (S)-Ethyl (3-methyl-4-oxo-5-(piperidin-1-yl)thiazolidin-2-ylidene)acetate; 5-Piperidin-1-yl-3-methyl-2-[(ethoxycarbonyl)methylene]-1,3-thiazolidin-4-one; (S)-enantiomer of Ethyl 2-(3-methyl-4-oxo-5-piperidino-2-thiazolidinylidene)acetate
EINECS	Contact for details

Quality Control

Our Ethyl (S)-(3-Methyl-4-Oxo-5-Piperidin-1-Ylthiazolidin-2-Ylidene)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (S-enantiomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.