Description

6-Fluoro-3-Piperidin-4-Yl-1H-Indole is a high-purity, advanced pharmaceutical intermediate featuring a unique indole-piperidine hybrid scaffold. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for synthesizing novel bioactive molecules. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing new therapeutic agents, particularly within the central nervous system (CNS) and oncology drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery.
• Kinase Inhibitor Development: Serves as a building block for potential kinase inhibitors due to its privileged heterocyclic structure.
• CNS Drug Discovery: Employed in the research of potential therapeutics for neurological and psychiatric disorders.
• Chemical Biology Probes: Utilized to develop tool compounds for studying biological targets and mechanisms.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthetic routes for clients.

Basic Information

Product Name	6-Fluoro-3-Piperidin-4-Yl-1H-Indole
CAS No.	76315-55-4
Molecular Formula	C13H15FN2
Molecular Weight	218.27 g/mol
Synonyms	6-Fluoro-3-(4-piperidinyl)-1H-indole; 3-(Piperidin-4-yl)-6-fluoro-1H-indole; 6-Fluoro-3-piperidin-4-ylindole; 1H-Indole, 6-fluoro-3-(4-piperidinyl)-; 6-Fluoro-3-(4-piperidyl)indole; 76315-55-4; 6-Fluoro-3-(piperidin-4-yl)-1H-indole
EINECS	Contact for details

Quality Control

Our 6-Fluoro-3-Piperidin-4-Yl-1H-Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical research. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic). Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.