Description

5-Bromo-2-Nitrothiophene is a versatile halogenated nitroheterocyclic compound that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both bromine and nitro substituents on a thiophene ring, makes it a valuable precursor for constructing complex molecules with tailored electronic and pharmaceutical properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in the development of antimicrobial, antiviral, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, leveraging its heterocyclic core for biological activity.
• Material Science Research: Serves as a monomer or building block for creating conjugated polymers and organic electronic materials like OLEDs and semiconductors.
• Dye and Pigment Manufacturing: Employed in the synthesis of specialized dyes and pigments due to the chromophoric nitro and thiophene groups.
• Ligand and Catalyst Development: Utilized in organometallic chemistry to create novel ligands for catalytic systems.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.

Basic Information

Product Name	5-Bromo-2-Nitrothiophene
CAS No.	76216-72-3
Molecular Formula	C4H2BrNO2S
Molecular Weight	208.03 g/mol
Synonyms	2-Nitro-5-bromothiophene; 5-Bromo-2-nitrothiophene; Thiophene, 5-bromo-2-nitro-; 5-Bromothiophene-2-nitrile; 2-Nitro-5-bromothiophene; 5-Bromo-2-nitro-thiophene
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Nitrothiophene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	68 - 72 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.