Description

3-[2-(2-Chlorophenyl)-5-(4-Methoxyphenyl)-3,4-Dihydropyrazol-3-Yl]-2-( 4-Methoxyphenyl)-1H-Indole is a complex heterocyclic organic compound featuring a fused indole and dihydropyrazole core structure. This compound is of significant interest as a key advanced pharmaceutical intermediate (API) in the research and development of novel therapeutic agents. Its unique molecular architecture makes it a valuable building block for medicinal chemists, particularly in the synthesis of compounds targeting central nervous system (CNS) disorders and other specialized applications. This high-purity chemical is essential for pharmaceutical R&D, process development, and scale-up activities in the life sciences sector.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for CNS-targeting drugs.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new therapeutic candidates.
• Process Chemistry & Scale-Up: Serves as a key material for optimizing synthetic routes and transitioning from laboratory to pilot and commercial-scale production.
• Biochemical Research: Employed as a probe or ligand in biochemical assays to study specific enzyme or receptor interactions.
• Contract Manufacturing (CMO/CDMO): Supplied to contract research and manufacturing organizations for custom synthesis projects.
• Academic Research: Utilized in university and institutional laboratories for advanced organic synthesis and drug discovery programs.

Basic Information

Product Name	3-[2-(2-Chlorophenyl)-5-(4-Methoxyphenyl)-3,4-Dihydropyrazol-3-Yl]-2-( 4-Methoxyphenyl)-1H-Indole
CAS No.	76195-71-6
Molecular Formula	C31H24ClN3O2
Molecular Weight	505.99 g/mol
Synonyms	76195-71-6; 1H-Indole, 3-[2-(2-chlorophenyl)-5-(4-methoxyphenyl)-3,4-dihydro-3-pyrazolyl]-2-(4-methoxyphenyl)-; 3-[2-(2-Chlorophenyl)-5-(4-Methoxyphenyl)-4,5-dihydro-1H-pyrazol-3-yl]-2-(4-methoxyphenyl)-1H-indole; 2-(4-Methoxyphenyl)-3-[5-(4-methoxyphenyl)-2-(2-chlorophenyl)-3,4-dihydropyrazol-3-yl]-1H-indole; (3RS)-3-[2-(2-Chlorophenyl)-5-(4-methoxyphenyl)-3,4-dihydropyrazol-3-yl]-2-(4-methoxyphenyl)-1H-indole
EINECS	Contact for details

Quality Control

Our high-purity pharmaceutical intermediate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, IR, MS), to ensure it meets the stringent requirements of research and development. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our quality commitment aligns with the standards expected for GMP-grade intermediates and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light). Ensure the storage area is well-ventilated and separate from incompatible materials. For long-term storage, consider under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.