Description

(R)-4-Bromo-α-Methylbenzyl Alcohol is a high-purity chiral building block of significant importance in asymmetric synthesis. This compound is valued for its role as a key intermediate in the production of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing enantiomerically pure products.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides, where the specific (R)-enantiomer can provide enhanced biological activity and environmental safety.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric transformations like hydrogenation and cross-coupling reactions.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high optical purity.
• Academic and R&D: Utilized in research laboratories for method development in asymmetric synthesis and stereochemistry studies.

Basic Information

Product Name	(R)-4-Bromo-α-Methylbenzyl Alcohol
CAS No.	76155-78-7
Molecular Formula	C9H11BrO
Molecular Weight	215.09 g/mol
Synonyms	(R)-1-(4-Bromophenyl)ethanol; (R)-α-Methyl-4-bromobenzyl alcohol; (R)-p-Bromo-α-methylbenzyl alcohol; (R)-4-Bromo-α-methylbenzenemethanol; (R)-(-)-1-(4-Bromophenyl)ethyl alcohol; (R)-1-(4-Bromophenyl)ethan-1-ol; (R)-4-Bromophenyl methyl carbinol
EINECS	Contact for details

Quality Control

Our (R)-4-Bromo-α-Methylbenzyl Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure compliance with high-purity standards for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing purity, identity, and chiral purity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.