Description

p-Bromospiperone is a high-purity brominated derivative of the butyrophenone class, serving as a critical intermediate in advanced pharmaceutical research and development. Its primary value lies in enabling the synthesis of novel compounds for neurological and psychiatric studies, particularly in the investigation of dopamine receptor interactions. This compound is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on developing next-generation therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential antipsychotic and neuroleptic drug candidates.
• Biochemical Research: Used as a reference standard and precursor in studies targeting dopamine D2 and serotonin 5-HT2A receptors.
• Medicinal Chemistry: Enables structure-activity relationship (SAR) studies for the development of new central nervous system (CNS) active molecules.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for pharmacological and neurological research programs.
• Reference Material: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Item	Details
Product Name	p-Bromospiperone
CAS No.	76139-30-5
Molecular Formula	C23H26BrFN2O2
Molecular Weight	461.37 g/mol
Synonyms	8-[4-(4-Bromophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one; 1'-(4-Bromobenzoyl)-4-phenylspiro[piperidine-4,4'(1'H)-imidazolidine]-2',5'-dione; Spiperone, 4'-bromo-; 4'-Bromospiperone; p-Bromo-spiperone; Br-Spiperone
EINECS	Contact for details

Quality Control

Our p-Bromospiperone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity determination and spectroscopic methods for structural confirmation. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.