Description

Benzyl Dichlorophosphite is a versatile organophosphorus reagent primarily used as a key intermediate in the synthesis of complex molecules. Its high reactivity makes it an essential building block for constructing phosphorus-containing compounds with precise stereochemistry and functionality. This product is critical for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-purity intermediates for advanced synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those containing phosphonate or phosphoramidate groups.
• Agrochemical Synthesis: Used in the production of advanced herbicides, insecticides, and plant growth regulators where phosphorus chemistry is central to the mode of action.
• Ligand and Catalyst Preparation: Serves as a starting material for the synthesis of chiral phosphite and phosphoramidite ligands used in asymmetric catalysis.
• Polymer Modification: Employed as a reactive monomer or cross-linking agent in the development of specialty polymers with flame-retardant or adhesive properties.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and organophosphorus chemistry.
• Nucleotide Chemistry: Potential use in the modification of nucleosides and the synthesis of oligonucleotide analogs for therapeutic applications.

Basic Information

Product Name	Benzyl Dichlorophosphite
CAS No.	76101-29-6
Molecular Formula	C7H7Cl2OP
Molecular Weight	209.01 g/mol
Synonyms	Benzyl Phosphorodichloridite; (Benzyloxy)dichlorophosphine; Dichloro(phenylmethoxy)phosphine; Phosphorodichlorous Acid Benzyl Ester; Benzyl Phosphorodichlorous Acid Ester; Phenylmethyl Dichlorophosphite; Benzyl Dichlorophosphonite; O-Benzyl Phosphorodichloridite
EINECS	Contact for details

Quality Control

Our Benzyl Dichlorophosphite is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. We employ advanced analytical techniques, including NMR, GC, and HPLC, to verify identity and assay. Certificates of Analysis (COA) detailing purity and impurity profiles are provided with each shipment. Our quality management system is designed to meet the stringent requirements of GMP and ISO standards for fine chemical production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at 2-8°C under an inert atmosphere (argon or nitrogen). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed and handled under dry conditions to prevent hydrolysis. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Purity (HPLC)	≥ 96.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.