Description

Methyl 5-(Aminomethyl)Thiophene-2-Carboxylate is a versatile heterocyclic building block featuring both an ester and a primary amine functional group. This bifunctional nature makes it a critical intermediate for synthesizing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical, agrochemical, and material science industries for constructing novel thiophene-based compounds, including active pharmaceutical ingredients (APIs) and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides that incorporate the thiophene moiety for enhanced activity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of conductive polymers, organic semiconductors, and specialty coatings.
• Ligand and Catalyst Development: The aminomethyl group allows for chelation to metals, making it useful for creating novel ligands in catalytic systems.
• Peptidomimetics and Bio-conjugation: The amine functionality enables its use in constructing peptide analogs or for linking molecules in bioconjugation chemistry.
• Chemical Research & Development: Employed as a versatile scaffold in medicinal chemistry and organic synthesis for library generation and structure-activity relationship (SAR) studies.

Basic Information

Product Name	Methyl 5-(Aminomethyl)Thiophene-2-Carboxylate
CAS No.	75985-18-1
Molecular Formula	C8H11NO2S
Molecular Weight	185.24 g/mol
Synonyms	5-(Aminomethyl)thiophene-2-carboxylic acid methyl ester; Methyl 5-aminomethyl-2-thiophenecarboxylate; 2-Thiophenecarboxylic acid, 5-(aminomethyl)-, methyl ester; 5-(Aminomethyl)-2-thiophenecarboxylic acid methyl ester; Methyl 5-aminomethylthiophene-2-carboxylate; 2-Carbomethoxy-5-aminomethylthiophene
EINECS	Contact for details

Quality Control

Our Methyl 5-(Aminomethyl)Thiophene-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed after use to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.