Description

2-Bromo-3-Methoxy-3-Methylbutanoic Acid is a specialized brominated carboxylic acid derivative that serves as a valuable chiral building block in advanced organic synthesis. Its unique structure, featuring both bromine and methoxy substituents, makes it a critical intermediate for constructing complex molecules with high stereochemical control. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of protease inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its halogenated structure contributes to biological activity.
• Asymmetric Synthesis: Employed as a precursor for generating other chiral compounds and auxiliaries due to its defined stereocenter.
• Material Science Research: Acts as a monomer or functionalization agent in the development of specialty polymers and advanced materials.
• Chemical Biology & Proteomics: Useful as a reactive handle or labeling agent in probe development for studying enzyme mechanisms and protein interactions.
• Academic & Contract Research: Serves as a valuable reagent in university laboratories and CROs (Contract Research Organizations) for methodological development and discovery chemistry.

Basic Information

Product Name	2-Bromo-3-Methoxy-3-Methylbutanoic Acid
CAS No.	75974-47-9
Molecular Formula	C7H13BrO3
Molecular Weight	225.08 g/mol
Synonyms	3-Methoxy-3-methyl-2-bromobutanoic acid; 2-Bromo-3-methoxy-3-methylbutyric acid; Butanoic acid, 2-bromo-3-methoxy-3-methyl-; α-Bromo-β-methoxy-β-methylbutyric acid; β-Methoxy-β-methyl-α-bromobutyric acid; (2R/S)-2-Bromo-3-methoxy-3-methylbutanoic acid (racemic mixture); Bromomethoxymethylbutanoic acid
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Methoxy-3-Methylbutanoic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and a Certificate of Analysis (COA) with every shipment, detailing key parameters such as assay, enantiomeric purity (if applicable), and impurity profiles. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature, containers should be amber glass or otherwise opaque.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.