Description

(R)-4-Chloro-α-Methylbenzyl Alcohol CAS NO 75968-40-0 is a high-purity chiral intermediate of significant importance in asymmetric synthesis. Its value lies in its role as a key building block for the production of enantiomerically pure pharmaceuticals and agrochemicals. This compound is essential for research and manufacturing chemists in the pharmaceutical, agrochemical, and fine chemical industries who require a reliable source of a specific stereoisomer to ensure the efficacy and safety of their final products.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting the central nervous system and cardiovascular diseases.
• Agrochemical Synthesis: Used in the production of enantiomerically pure pesticides and herbicides, where the specific stereochemistry is crucial for biological activity and environmental safety.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and catalysts used in asymmetric hydrogenation and other stereoselective transformations.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require high optical purity.
• Academic and R&D: A valuable reagent for research in organic chemistry, medicinal chemistry, and process development within university and corporate laboratories.

Basic Information

Product Name	(R)-4-Chloro-α-Methylbenzyl Alcohol
CAS No.	75968-40-0
Molecular Formula	C8H9ClO
Molecular Weight	156.61 g/mol
Synonyms	(R)-1-(4-Chlorophenyl)ethanol; (R)-α-Methyl-4-chlorobenzyl Alcohol; (R)-4-Chloro-α-methylbenzyl Alcohol; (R)-p-Chloro-α-methylbenzyl Alcohol; (R)-1-(4-Chlorophenyl)ethyl Alcohol; (R)-4-Chlorophenylmethylcarbinol; (R)-(-)-1-(4-Chlorophenyl)ethanol; (R)-4-Chloro-α-methylbenzenemethanol
EINECS	Contact for details

Quality Control

Our (R)-4-Chloro-α-Methylbenzyl Alcohol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, to ensure it meets the high-purity standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.