Description

6-Amino-1H-Indazole-5-Carboxylic Acid is a high-purity, multifunctional heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals, offering a versatile scaffold for medicinal chemistry. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, anticancer agents, and other biologically active small molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a building block for advanced polymers, ligands for catalysis, and organic electronic materials.
• Bioconjugation & Probe Development: The carboxylic acid and amino groups allow for facile conjugation to peptides, proteins, or fluorescent tags for diagnostic applications.
• Chemical Biology: Employed in fragment-based drug discovery and as a core structure for designing chemical probes to study biological pathways.

Basic Information

Product Name	6-Amino-1H-Indazole-5-Carboxylic Acid
CAS No.	75844-33-6
Molecular Formula	C8H7N3O2
Molecular Weight	177.16 g/mol
Synonyms	5-Carboxy-6-aminoindazole; 6-Amino-1H-indazole-5-carboxylic acid; 1H-Indazole-5-carboxylic acid, 6-amino-; 6-Aminoindazole-5-carboxylic acid; 5-Amino-1H-indazole-6-carboxylic acid (tautomer); 6-Amino-1H-indazol-5-carboxylic acid; 75844-33-6; AI5CA
EINECS	Contact for details

Quality Control

Our 6-Amino-1H-Indazole-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance with research and cGMP-grade requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.