Description

2-Iodo-1-Methyl-1H-Indole is a halogenated indole derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and valuable building block for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. Its primary value lies in enabling key coupling reactions and serving as a precursor for active pharmaceutical ingredients (APIs). This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new generation herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of organic electronic materials and advanced polymers.
• Cross-Coupling Reactions: An effective substrate in palladium-catalyzed reactions such as Suzuki, Sonogashira, and Heck couplings for carbon-carbon bond formation.
• Ligand and Catalyst Development: Utilized to create novel nitrogen-containing ligands for transition metal catalysis.
• Academic & Contract Research: A valuable reagent for methodological studies and exploring new synthetic pathways in university and CRO laboratories.

Basic Information

Item	Details
Product Name	2-Iodo-1-Methyl-1H-Indole
CAS No.	75833-63-5
Molecular Formula	C9H8IN
Molecular Weight	257.07 g/mol
Synonyms	1-Methyl-2-iodoindole; 2-Iodo-1-methylindole; 1-Methyl-2-iodo-1H-indole; 2-Iodo-N-methylindole; 1H-Indole, 2-iodo-1-methyl-; Iodomethylindole; 2-Iodo-1-methylindole; N-Methyl-2-iodoindole
EINECS	Contact for details

Quality Control

Every batch of 2-Iodo-1-Methyl-1H-Indole is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging are performed under controlled lighting conditions to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.