Description

5-Nitroisoquinoline-1-Carboxylic Acid is a high-purity, versatile chemical intermediate of significant importance in advanced organic synthesis. Its core value lies in its functionalized isoquinoline scaffold, which serves as a critical building block for constructing complex molecules with targeted biological activity. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological disorders, oncology, and infectious diseases.
• Agrochemical Research: Used to develop new herbicides, fungicides, and insecticides by providing a nitro-substituted heterocyclic core for structure-activity relationship (SAR) studies.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Precursor: Employed in the research and development of advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers.
• Chemical Biology Probe Synthesis: Utilized to build molecular probes for studying enzyme function and biological pathways in academic and industrial R&D settings.

Basic Information

Product Name	5-Nitroisoquinoline-1-Carboxylic Acid
CAS No.	75795-40-3
Molecular Formula	C₁₀H₆N₂O₄
Molecular Weight	218.17 g/mol
Synonyms	1-Isoquinolinecarboxylic acid, 5-nitro-; 5-Nitro-1-isoquinolinecarboxylic acid; 5-Nitroisoquinoline-1-carboxylic acid; 1-Carboxy-5-nitroisoquinoline; 5-Nitro-isoquinolin-1-carbonsäure (German); Acide 5-nitro-isoquinoléine-1-carboxylique (French); 5-Nitro-1-isoquinolinylcarboxylic acid; 75795-40-3
EINECS	Contact for details

Quality Control

Every batch of 5-Nitroisoquinoline-1-Carboxylic Acid is produced and tested under a strict quality management system. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) documenting purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.