Description

Hexadecanoic-7,7,8,8-D4 Acid is a stable isotope-labeled analog of palmitic acid, where four hydrogen atoms are replaced by deuterium at specific positions. This compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring high accuracy and reproducibility in analytical measurements. It is primarily needed by researchers and quality control laboratories in the pharmaceutical, metabolic research, and analytical chemistry industries for precise tracer studies and method validation.

Application

• Internal Standard for Mass Spectrometry (MS): Used for the accurate quantification of palmitic acid and related metabolites in biological samples via GC-MS or LC-MS.
• Metabolic Pathway Tracing: Enables detailed studies of lipid metabolism, β-oxidation, and fatty acid synthesis in biomedical and nutritional research.
• Pharmaceutical Impurity Profiling: Assists in the identification and quantification of process-related impurities or degradants in drug substances and products.
• Clinical Diagnostics: Supports the development of diagnostic assays for metabolic disorders by providing a stable reference point.
• Biomarker Discovery & Validation: Critical in proteomics and metabolomics for the relative and absolute quantification of lipid biomarkers.
• Food & Nutritional Science: Applied in research on fat absorption, digestion, and the metabolic fate of dietary lipids.

Basic Information

Product Name	Hexadecanoic-7,7,8,8-D4 Acid
CAS No.	75736-49-1
Molecular Formula	C16H28D4O2
Molecular Weight	260.44 g/mol
Synonyms	Palmitic Acid-d4; Palmitic-7,7,8,8-d4 Acid; Hexadecanoic-d4 Acid; n-Hexadecanoic-7,7,8,8-d4 Acid; 1-Pentadecanecarboxylic-7,7,8,8-d4 Acid; C16:0-d4; Deuterated Palmitic Acid; [7,7,8,8-2H4]Hexadecanoic Acid
EINECS	Contact for details

Quality Control

Our Hexadecanoic-7,7,8,8-D4 Acid is manufactured under strict quality systems to ensure exceptional isotopic purity and chemical stability. Each batch is characterized by advanced spectroscopic and chromatographic techniques, including NMR and HPLC-MS, to confirm isotopic enrichment and chemical purity. A comprehensive Certificate of Analysis (COA) detailing assay, isotopic purity, and impurity profile is provided with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0% (Chemical Purity)
Isotopic Purity (NMR/MS)	≥ 98 atom % D
Chemical Purity (GC/HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.