Description

Hexadecanoic-5,5,6,6-D4 Acid CAS NO 75736-47-9 is a deuterium-labeled analog of palmitic acid, a key saturated fatty acid, where four hydrogen atoms are replaced with deuterium at specific positions. This isotopic labeling is critical for creating internal standards in mass spectrometry, enabling highly accurate quantitative analysis in complex biological and chemical matrices. It is an essential reagent for researchers and quality control laboratories in the pharmaceutical, metabolomics, and analytical chemistry sectors who require precise measurement and traceability.

Application

• Internal Standard for Mass Spectrometry (MS): Serves as a critical quantitative reference standard in GC-MS and LC-MS analyses for palmitic acid and related metabolites.
• Pharmaceutical Research & Development: Used in pharmacokinetic (PK) and pharmacodynamic (PD) studies to track drug metabolism and lipid pathways.
• Metabolomics & Lipidomics: Enables precise quantification of palmitic acid and its derivatives in biological samples (e.g., plasma, tissue, cells) for disease biomarker discovery.
• Clinical Diagnostics: Facilitates accurate measurement of fatty acid profiles in nutritional and metabolic disorder testing.
• Stable Isotope Labeling: Acts as a starting material or tracer in the synthesis of more complex deuterated compounds for mechanistic studies.
• Food & Nutritional Science: Used in research to analyze fat content, absorption, and metabolism in food products and dietary studies.
• Quality Control & Method Validation: Essential for developing and validating robust analytical methods in contract research organizations (CROs) and regulatory environments.

Basic Information

Product Name	Hexadecanoic-5,5,6,6-D4 Acid
CAS No.	75736-47-9
Molecular Formula	C16H28D4O2
Molecular Weight	260.44 g/mol
Synonyms	Palmitic-5,5,6,6-d4 Acid; [5,5,6,6-2H4]Hexadecanoic Acid; Hexadecanoic-d4 Acid (position specific); 1-Pentadecanecarboxylic-5,5,6,6-d4 Acid; C16:0-d4; Deuterated Palmitic Acid; Isotopic Palmitic Acid; n-Hexadecanoic-d4 Acid
EINECS	Contact for details

Quality Control

Our deuterated compounds are produced and controlled under a strict quality management system. Each batch of Hexadecanoic-5,5,6,6-D4 Acid is analyzed to confirm isotopic purity (D-enrichment), chemical purity, and identity. We provide comprehensive Certificates of Analysis (COA) with data from NMR, MS, and HPLC, ensuring traceability and compliance with research and regulatory requirements. Specifications are tailored to meet the stringent needs of analytical and pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C or as specified on the label or COA. This material is easily oxidized; for long-term storage, consider under an inert atmosphere such as argon or nitrogen. Keep the container in a cool, dry, and well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Assay (HPLC)	≥98.0% (chemical purity)
Isotopic Purity (NMR/MS)	≥98 atom % D (at specified positions)
Melting Point	61 - 64 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.