Description

Methyl 4-Methyl-5-Nitrothiophene-2-Carboxylate is a high-purity, specialized heterocyclic building block essential for advanced organic synthesis. This compound matters as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its unique thiophene and nitro-substituted structure enables critical transformations. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), functional materials, and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Serves as a key building block for developing advanced herbicides and fungicides with novel modes of action.
• Material Science Research: Used in the development of organic semiconductors, conductive polymers, and other functional materials due to its electron-deficient thiophene core.
• Chemical Biology & Proteomics: Employed as a specialty reagent for creating molecular probes and tags for studying biological systems.
• Academic & Industrial R&D: A valuable compound for methodological research in organic chemistry, including studies on nitration, esterification, and heterocyclic chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	Methyl 4-Methyl-5-Nitrothiophene-2-Carboxylate
CAS No.	75735-47-6
Molecular Formula	C7H7NO4S
Molecular Weight	201.20 g/mol
Synonyms	5-Nitro-4-methylthiophene-2-carboxylic acid methyl ester; Methyl 5-nitro-4-methyl-2-thiophenecarboxylate; 2-Thiophenecarboxylic acid, 4-methyl-5-nitro-, methyl ester; 4-Methyl-5-nitrothiophene-2-carboxylic acid methyl ester; Methyl 4-methyl-5-nitro-2-thiophenecarboxylate; 5-Nitro-4-methyl-2-thiophenecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 4-Methyl-5-Nitrothiophene-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.