Description

3-Nitrothiophene-2-Carboxylic Acid Methyl Ester is a high-purity, specialized organic building block crucial for advanced chemical synthesis. This compound serves as a key intermediate in the development of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing functionalized thiophene cores.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides where the nitro-thiophene moiety imparts specific biological activity.
• Material Science: Serves as a monomer or building block for creating specialized polymers and organic electronic materials with unique optoelectronic properties.
• Chemical Synthesis: Employed in organic synthesis as a versatile electrophile for nucleophilic substitution reactions or as a substrate for further functionalization of the thiophene ring.
• Dye & Pigment Intermediate: Utilized in the production of specialized dyes and pigments where the nitro and ester groups allow for color tuning and property modification.

Basic Information

Product Name	3-Nitrothiophene-2-Carboxylic Acid Methyl Ester
CAS No.	75735-44-3
Molecular Formula	C6H5NO4S
Molecular Weight	187.17 g/mol
Synonyms	Methyl 3-nitrothiophene-2-carboxylate; 2-Thiophenecarboxylic acid, 3-nitro-, methyl ester; 3-Nitro-2-thiophenecarboxylic acid methyl ester; Methyl 3-nitro-2-thiophenecarboxylate; 3-Nitrothiophene-2-methyl carboxylate; 75735-44-3; 3-Nitro-thiophene-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 3-Nitrothiophene-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment ensures the material is suitable for demanding applications in research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.