Description

Tobuterol is a selective β2-adrenergic receptor agonist, a key pharmaceutical intermediate in the synthesis of advanced bronchodilators. Its primary value lies in its role as a critical building block for developing active pharmaceutical ingredients (APIs) targeting respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). This high-purity compound is essential for pharmaceutical R&D laboratories, process development chemists, and manufacturers specializing in respiratory therapeutics.

Application

• Pharmaceutical Intermediate: Primary use as a key synthetic precursor in the manufacture of bronchodilator Active Pharmaceutical Ingredients (APIs).
• Respiratory Drug R&D: Critical building block in research and development of new β2-agonist therapies for asthma and COPD.
• Process Chemistry & Scale-Up: Used in optimizing synthetic routes and scaling production from laboratory to commercial batch sizes.
• Reference Standard: Serves as an analytical standard for quality control and method validation in pharmaceutical manufacturing.
• Academic & Institutional Research: Utilized in pharmacological studies investigating adrenergic receptor mechanisms and signaling pathways.

Basic Information

Product Name	Tobuterol
CAS No.	75626-99-2
Molecular Formula	C₁₃H₂₀N₂O₃
Molecular Weight	252.31 g/mol
Synonyms	1-(3,5-Dihydroxyphenyl)-2-(tert-butylamino)ethanol; Tobuterol Hydrochloride (salt form); α-[(tert-Butylamino)methyl]-3,5-dihydroxybenzyl alcohol; KWD-2183; β2-Adrenergic agonist intermediate; 3,5-Dihydroxy-α-[(1,1-dimethylethyl)amino]methyl]benzenemethanol
EINECS	Contact for details

Quality Control

Our Tobuterol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation via IR and NMR, and residual solvent analysis to ensure it meets stringent standards for pharmaceutical intermediate use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5%
Any single unknown impurity	≤0.5%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.