Description

4-Phenyl-1,2,3,4-Tetrahydroisoquinoline Hydrochloride is a high-purity organic salt compound, serving as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis. Its value lies in its unique tetrahydroisoquinoline scaffold, which is a privileged structure found in numerous bioactive molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries, particularly for the development of new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential central nervous system (CNS) active drugs, alkaloid derivatives, and other pharmacologically active compounds.
• Organic Synthesis Research: A versatile precursor for constructing complex nitrogen-containing heterocycles and exploring novel chemical reactions in academic and industrial R&D.
• Agrochemical Development: Used in the research and synthesis of novel pesticides and herbicides that leverage the isoquinoline structure.
• Fine Chemical Production: Intermediate in the manufacture of dyes, pigments, and other specialty chemicals requiring the phenyl-tetrahydroisoquinoline moiety.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	4-Phenyl-1,2,3,4-Tetrahydroisoquinoline Hydrochloride
CAS No.	75626-12-9
Molecular Formula	C₁₅H₁₅N·HCl
Molecular Weight	245.75 g/mol
Synonyms	4-Phenyl-1,2,3,4-tetrahydroisoquinoline HCl; 4-Phenyl-1,2,3,4-tetrahydroisoquinoline hydrochloride; 1,2,3,4-Tetrahydro-4-phenylisoquinoline hydrochloride; 4-Phenyl-3,4-dihydro-1H-isoquinoline hydrochloride; 4-Phenyl-THIQ HCl; 4-Phenyl-1,2,3,4-tetrahydroisoquinolinium chloride
EINECS	Contact for details

Quality Control

Our 4-Phenyl-1,2,3,4-Tetrahydroisoquinoline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.