Description

Diphenyl Succinimidyl Phosphate is a high-purity, reactive chemical intermediate primarily used in bioconjugation and peptide synthesis. This compound is critical for introducing phosphate ester groups or acting as a coupling agent in the formation of amide bonds under mild conditions. It is an essential reagent for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require precise and efficient chemical modifications.

Application

• Peptide Synthesis: Acts as a key phosphorylating or activating agent in solid-phase and solution-phase peptide synthesis.
• Bioconjugation: Used to label proteins, antibodies, and other biomolecules with phosphate tags or to cross-link molecules for diagnostic and therapeutic applications.
• Phosphorylation Reagent: Employed in organic synthesis to introduce phosphate ester protecting groups onto alcohols, sugars, and nucleosides.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the synthesis of specialized polymers and hydrogels for biomedical engineering.
• Chemical Biology Research: A valuable tool for studying phosphorylation events, signal transduction pathways, and enzyme mechanisms in vitro.
• Intermediate for API Synthesis: Used in the multistep synthesis of complex active pharmaceutical ingredients (APIs) that require phosphate-containing motifs.

Basic Information

Product Name	Diphenyl Succinimidyl Phosphate
CAS No.	75513-55-2
Molecular Formula	C₁₆H₁₄NO₆P
Molecular Weight	347.26 g/mol
Synonyms	Diphenyl (2,5-dioxopyrrolidin-1-yl) phosphate; Succinimidyl diphenyl phosphate; NSC 334368; 1-[(Diphenoxyphosphoryl)oxy]pyrrolidine-2,5-dione; Diphenylphosphoryl succinimide; O,O-Diphenyl N-succinimidyl phosphate; Phosphoric acid, diphenyl ester, 2,5-dioxo-1-pyrrolidinyl ester
EINECS	Contact for details

Quality Control

Our Diphenyl Succinimidyl Phosphate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide comprehensive Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.