Description

2-Nitrothiophene-4-Carboxaldehyde is a versatile heterocyclic building block and key synthetic intermediate. This compound matters for its role as a crucial precursor in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel thiophene-based scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing functionalized thiophene rings.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the nitro and aldehyde groups offer sites for further chemical modification.
• Material Science Research: Serves as a building block for creating advanced organic materials, such as conductive polymers, organic semiconductors, and non-linear optical (NLO) materials.
• Dye and Pigment Manufacturing: Employed in the synthesis of specialized dyes and pigments, leveraging the thiophene backbone for color and stability properties.
• Ligand and Catalyst Development: Useful for constructing complex ligands in coordination chemistry and catalysis due to its multifunctional nature.
• Academic and R&D Laboratories: A valuable reagent for methodological studies and the exploration of new heterocyclic chemistry and reaction pathways.

Basic Information

Product Name	2-Nitrothiophene-4-Carboxaldehyde
CAS No.	75428-45-4
Molecular Formula	C5H3NO3S
Molecular Weight	157.15 g/mol
Synonyms	4-Formyl-2-nitrothiophene; 2-Nitro-4-thiophenecarboxaldehyde; 2-Nitrothiophene-4-carbaldehyde; 4-Thiophenecarboxaldehyde, 2-nitro-; 2-Nitro-4-formylthiophene; 4-Aldehyde-2-nitrothiophene
EINECS	Contact for details

Quality Control

Our 2-Nitrothiophene-4-Carboxaldehyde is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.