Description

8-Chloro-1,2,3,4-Tetrahydro-Isoquinoline is a versatile heterocyclic organic compound that serves as a critical synthetic intermediate in advanced chemical manufacturing. Its value lies in its unique fused-ring structure, which provides a privileged scaffold for constructing complex molecules with targeted biological activity. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides.
• Chemical Research & Development: Serves as a versatile precursor for exploring new chemical entities and reaction pathways in organic chemistry.
• Material Science: Investigated as a monomer or precursor for specialty polymers and advanced organic materials.
• Academic & Contract Research: Utilized in university and CRO laboratories for medicinal chemistry programs and methodological studies.

Basic Information

Product Name	8-Chloro-1,2,3,4-Tetrahydro-Isoquinoline
CAS No.	75416-50-1
Molecular Formula	C9H10ClN
Molecular Weight	167.63 g/mol
Synonyms	8-Chloro-1,2,3,4-tetrahydroisoquinoline; 8-Chloro-3,4-dihydro-1H-isoquinoline; 1,2,3,4-Tetrahydro-8-chloroisoquinoline; 8-Chloro-THIQ; 8-Cl-THIQ
EINECS	Contact for details

Quality Control

Our 8-Chloro-1,2,3,4-Tetrahydro-Isoquinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed results from HPLC, GC, NMR, and other relevant techniques. Our quality commitment supports your regulatory and research needs for reliable, high-grade chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.