Description

Nikkomycin B(X) CAS NO 75410-71-8 is a potent nucleoside-peptide antibiotic belonging to the nikkomycin family, which acts as a competitive inhibitor of chitin synthase. This compound matters for its targeted antifungal activity, offering a specific mode of action against chitin-containing fungi. It is needed by researchers in pharmaceutical development for novel antifungal agents and by agricultural scientists exploring eco-friendly fungicides for crop protection.

Application

• Antifungal Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) in the discovery and study of new antifungal therapeutics.
• Agricultural Fungicide Studies: Investigated for its potential in formulating biocontrol agents to manage fungal pathogens in crops, leveraging its specific chitin synthesis inhibition.
• Biochemical Pathway Analysis: Used as a precise tool to study the chitin biosynthesis pathway in fungi, yeast, and insects in academic and industrial laboratories.
• Veterinary Medicine: Explored for applications in treating fungal infections in animals, given its targeted mechanism of action.
• Enzyme Inhibition Assays: Employed in high-throughput screening and enzymatic assays to identify and characterize chitin synthase inhibitors.

Basic Information

Product Name	Nikkomycin B(X)
CAS No.	75410-71-8
Molecular Formula	C20H25N5O10
Molecular Weight	495.44 g/mol
Synonyms	Nikkomycin BX; Nikkomycin X; Antibiotic BX 1-A; 5-[(2-Amino-4-hydroxy-4-oxobutanoyl)amino]-1-(5-amino-5-deoxy-D-allofuranuronosyl)-1H-imidazole-4-carboxamide; 1-(5-Amino-5-deoxy-D-allofuranuronosyl)-5-[(2-amino-4-hydroxy-4-oxobutanoyl)amino]-1H-imidazole-4-carboxamide; Nikkomycin B (X component); Paulomycin BX
EINECS	Contact for details

Quality Control

Our Nikkomycin B(X) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-purity standards suitable for research and development. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%
Biological Activity	Assay available upon request

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.