Description

4-(4-Chlorophenyl)-2-Methyl-3-Butyn-2-Ol is a versatile organic intermediate featuring both an aromatic chlorophenyl group and a terminal alkyne functionality. This unique structure makes it a valuable building block for synthesizing more complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the fine chemical and life sciences industries. The compound's reactivity allows for selective modifications, enabling the creation of novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the chlorophenyl moiety for bioactivity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Ligand and Catalyst Development: The alkyne group is instrumental in creating complex ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying biological pathways and protein interactions via click chemistry.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects undertaken by CDMOs (Contract Development and Manufacturing Organizations).

Basic Information

Product Name	4-(4-Chlorophenyl)-2-Methyl-3-Butyn-2-Ol
CAS No.	75373-70-5
Molecular Formula	C11H11ClO
Molecular Weight	194.66 g/mol
Synonyms	4-(4-Chlorophenyl)-2-methylbut-3-yn-2-ol; 2-Methyl-4-(4-chlorophenyl)-3-butyn-2-ol; 1-(4-Chlorophenyl)-3-methyl-1-butyn-3-ol; 3-Butyn-2-ol, 4-(4-chlorophenyl)-2-methyl-; 4-(p-Chlorophenyl)-2-methyl-3-butyn-2-ol
EINECS	Contact for details

Quality Control

Our 4-(4-Chlorophenyl)-2-Methyl-3-Butyn-2-Ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (by HPLC), impurity profile, and physical characteristics. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.