Description

5‐Benzyloxytryptophol‐α,α,β,β‐D4 is a deuterium-labeled derivative of benzyloxytryptophol, a compound of significant interest in biochemical and pharmacological research. This isotopically labeled version is specifically designed for use as an internal standard in mass spectrometry-based analytical methods, providing enhanced accuracy and reliability in quantitative analysis. It is an essential tool for researchers and analytical laboratories in the pharmaceutical, biotechnology, and contract research organization (CRO) sectors who require precise measurement of metabolites or related compounds in complex biological matrices.

Application

• Internal Standard for LC-MS/MS: Primary application as a stable, non-interfering internal standard for the accurate quantification of benzyloxytryptophol and its analogs in bioanalytical studies.
• Pharmacokinetic & Metabolic Studies: Enables precise tracking of drug absorption, distribution, metabolism, and excretion (ADME) for novel therapeutic agents.
• Biomarker Research: Facilitates the development and validation of sensitive assays for potential biomarkers in clinical and preclinical samples.
• Drug Discovery & Development: Used in high-throughput screening and lead optimization phases to ensure data integrity in quantitative analyses.
• Forensic & Clinical Toxicology: Supports the development of confirmatory methods for the detection of specific compounds or their metabolites in forensic casework.
• Isotope Dilution Mass Spectrometry (IDMS): Serves as the ideal spike-in standard for this gold-standard quantitative technique due to its defined deuterium content.

Basic Information

Product Name	5‐Benzyloxytryptophol‐α,α,β,β‐D4
CAS No.	75238-47-0
Molecular Formula	C₁₇H₁₃D₄NO₂
Molecular Weight	~ 283.36 g/mol
Synonyms	5-(Benzyloxy)-1H-indole-3-ethanol-α,α,β,β-d4; 5-(Benzyloxy)tryptophol-d4; 2-[5-(Benzyloxy)-1H-indol-3-yl]ethan-1,1,2,2-d4-ol; Benzyloxytryptophol-d4; Deuterated Benzyloxytryptophol; 5-O-Benzyltryptophol-d4; 5-BOT-d4; Internal Standard for Benzyloxytryptophol
EINECS	Contact for details

Quality Control

Every batch of 5‐Benzyloxytryptophol‐α,α,β,β‐D4 is manufactured and analyzed under strict quality protocols to ensure the highest standards of isotopic purity and chemical identity, which are critical for its function as an analytical standard. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request and provide detailed results for key parameters including isotopic enrichment, chemical purity, and identity confirmation.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This product is light-sensitive (store away from light). For long-term storage, consider storing desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.