Description

(3R,4R)-1-Benzyl-3,4-Dihydroxypyrrolidine-2,5-Dione is a chiral, functionalized pyrrolidine derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of pharmaceuticals and bioactive molecules, particularly those requiring precise stereochemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of complex drug candidates, chiral catalysts, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), especially in areas like enzyme inhibitors and receptor modulators.
• Asymmetric Synthesis: Utilized as a precursor or auxiliary in the construction of complex, stereodefined molecules for medicinal chemistry and total synthesis projects.
• Biochemical Research: Serves as a scaffold or reference standard in biochemical studies investigating enzyme mechanisms or protein-ligand interactions.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals, including advanced materials and performance chemicals where specific chirality is required.
• Academic & Industrial R&D: Used in laboratory-scale research for method development and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	(3R,4R)-1-Benzyl-3,4-Dihydroxypyrrolidine-2,5-Dione
CAS No.	75172-31-5
Molecular Formula	C11H11NO4
Molecular Weight	221.21 g/mol
Synonyms	(3R,4R)-1-Benzyl-3,4-dihydroxy-2,5-pyrrolidinedione; 1-Benzyl-3,4-dihydroxy-(3R,4R)-pyrrolidine-2,5-dione; (3R,4R)-1-Benzyl-3,4-dihydroxysuccinimide; (3R,4R)-1-Benzyl-3,4-dihydroxy-2,5-diketopyrrolidine; 1-Benzyl-3,4-dihydroxy-D-erythro-2,5-pyrrolidinedione; 75172-31-5; (3R,4R)-1-Bn-3,4-dihydroxypyrrolidine-2,5-dione
EINECS	Contact for details

Quality Control

Our (3R,4R)-1-Benzyl-3,4-Dihydroxypyrrolidine-2,5-Dione is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.