Description

(3R,4S)-1-Benzyl-3,4-Dihydroxy-2,5-Pyrrolidinedione is a chiral pyrrolidinedione derivative, a high-value synthetic intermediate prized for its stereochemically defined functional groups. This compound matters for its role in the asymmetric synthesis of complex molecules, particularly in pharmaceutical research and development. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of potential drug candidates, especially those targeting neurological and metabolic disorders.
• Asymmetric Catalyst Ligand Precursor: Used in the development of novel chiral ligands for metal-catalyzed asymmetric reactions.
• Agrochemical Synthesis: Intermediate in the production of advanced, stereospecific pesticides and herbicides.
• Fine Chemical Research: Serves as a starting material or intermediate in academic and industrial research for novel organic compounds.
• Protease Inhibitor Scaffold: Core structure for designing inhibitors of specific enzymes like dipeptidyl peptidase.

Basic Information

Product Name	(3R,4S)-1-Benzyl-3,4-Dihydroxy-2,5-Pyrrolidinedione
CAS No.	75112-74-2
Molecular Formula	C11H11NO4
Molecular Weight	221.21 g/mol
Synonyms	1-Benzyl-3,4-dihydroxy-2,5-pyrrolidinedione; (3R,4S)-1-Benzyl-3,4-dihydroxypyrrolidine-2,5-dione; 1-Benzyl-3,4-dihydroxysuccinimide; (3R,4S)-1-Benzyl-3,4-dihydroxytetrahydro-1H-pyrrole-2,5-dione; (3R,4S)-1-Benzyl-3,4-dihydroxy-2,5-dioxopyrrolidine; 3,4-Dihydroxy-1-benzyl-2,5-pyrrolidinedione; (3R,4S)-1-Benzyl-3,4-dihydroxy-N-benzylsuccinimide
EINECS	Contact for details

Quality Control

Our (3R,4S)-1-Benzyl-3,4-Dihydroxy-2,5-Pyrrolidinedione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.