Description

2-Trimethylsiloxy-1,1,1,5,5,5-Hexafluoropent-2-Ene-4-One is a specialized fluorinated silyl enol ether, a high-value intermediate in advanced organic synthesis. Its core value lies in its unique reactivity profile, enabling efficient introduction of fluorinated ketone moieties under mild conditions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated drug candidates, including protease inhibitors and kinase inhibitors.
• Agrochemical Synthesis: Used in the production of advanced, fluorinated pesticides and herbicides with enhanced efficacy and environmental profiles.
• Material Science: Precursor for fluorinated polymers and specialty materials with unique surface properties and chemical resistance.
• Organic Synthesis Reagent: Acts as a versatile reagent for nucleophilic trifluoroacetylation and other fluorination reactions in complex molecule construction.
• Liquid Crystal & Electronic Chemicals: Intermediate in the synthesis of fluorinated components for display technologies and electronic materials.

Basic Information

Product Name	2-Trimethylsiloxy-1,1,1,5,5,5-Hexafluoropent-2-Ene-4-One
CAS No.	75108-40-6
Molecular Formula	C8H9F6O2Si
Molecular Weight	279.23 g/mol
Synonyms	1,1,1,5,5,5-Hexafluoro-2-(trimethylsiloxy)-2-penten-4-one; 2-(Trimethylsiloxy)-1,1,1,5,5,5-hexafluoropent-2-en-4-one; 4,4,4-Trifluoro-1-(trimethylsiloxy)-1-(trifluoromethyl)-1,3-butadien-2-one; TMS Enol Ether of Hexafluoroacetylacetone; HFAA-TMS Enol Ether; (E)-1,1,1,5,5,5-Hexafluoro-4-oxopent-2-en-2-yloxy-trimethylsilane
EINECS	Contact for details

Quality Control

Every batch of 2-Trimethylsiloxy-1,1,1,5,5,5-Hexafluoropent-2-Ene-4-One is produced and tested under strict quality management systems. We ensure high purity and consistency through advanced analytical techniques including GC, HPLC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent moisture absorption and decomposition. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.