Description

4-Iodo-1-Methyl-1H-Pyrazole-5-Carboxylic Acid is a versatile and high-value iodinated pyrazole derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a carboxylic acid and an iodine substituent, makes it an essential building block for constructing complex molecules with tailored properties. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition or receptor modulation.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the pyrazole core is a common pharmacophore.
• Ligand Synthesis: Employed for creating specialized ligands in coordination chemistry and catalysis due to its carboxylic acid functionality.
• Material Science: Serves as a monomer or functionalizing agent in the production of advanced polymers and organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes, leveraging the iodine atom for potential labeling or cross-linking.
• Custom Synthesis & Scale-Up: A fundamental starting material for contract research and manufacturing organizations (CROs/CMOs) providing bespoke chemical synthesis services.

Basic Information

Product Name	4-Iodo-1-Methyl-1H-Pyrazole-5-Carboxylic Acid
CAS No.	75092-30-7
Molecular Formula	C5H5IN2O2
Molecular Weight	251.01 g/mol
Synonyms	1-Methyl-4-iodo-1H-pyrazole-5-carboxylic acid; 4-Iodo-1-methyl-1H-pyrazole-5-carboxylic acid; 5-Carboxy-1-methyl-4-iodopyrazole; 1-Methyl-4-iodopyrazole-5-carboxylic acid; 4-Iodo-1-methylpyrazole-5-carboxylic acid; 75092-30-7; AI3-52362
EINECS	Contact for details

Quality Control

Our 4-Iodo-1-Methyl-1H-Pyrazole-5-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.